{"id":2345,"date":"2026-03-04T17:03:36","date_gmt":"2026-03-04T08:03:36","guid":{"rendered":"https:\/\/chiken-net.site\/column\/?p=2345"},"modified":"2026-04-23T06:07:32","modified_gmt":"2026-04-22T21:07:32","slug":"clinical-trial-7puq","status":"publish","type":"post","link":"https:\/\/chiken-net.site\/column\/clinical-trial-7puq\/","title":{"rendered":"\u300e\u5065\u5eb7\u306a\u306e\u306b\u6cbb\u9a13\u306b\u843d\u3061\u305f\u300f\u3042\u306a\u305f\u3078\u3002\u53c2\u52a0\u3067\u304d\u306a\u304410\u306e\u7406\u7531\u3068\u3001\u305d\u306e\u88cf\u306b\u3042\u308b\u79d1\u5b66\u7684\u771f\u5b9f"},"content":{"rendered":"\n<p>\u300c\u6cbb\u9a13\u30e2\u30cb\u30bf\u30fc\u300d\u3084\u300c\u6cbb\u9a13\u30dc\u30e9\u30f3\u30c6\u30a3\u30a2\u300d\u306b\u8208\u5473\u3092\u6301\u3063\u305f\u3082\u306e\u306e\u3001\u5065\u5eb7\u3068\u81ea\u8a8d\u3057\u3066\u3044\u3066\u3082\u3001\u5065\u5eb7\u306a\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8a66\u9a13\u3067\u4e0d\u5408\u683c\u306b\u306a\u3063\u305f\u7d4c\u9a13\u306f\u3042\u308a\u307e\u305b\u3093\u304b\uff1f\u5b9f\u306f\u3001\u6cbb\u9a13\u306f\u3001\u53c2\u52a0\u3092\u5e0c\u671b\u3057\u305f\u304b\u3089\u3068\u3044\u3063\u3066\u5168\u54e1\u304c\u53c2\u52a0\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u4e00\u5b9a\u6570\u306e\u5fd7\u9858\u8005\u304c\u4e0d\u9069\u683c\u3068\u5224\u65ad\u3055\u308c\u308b\u73fe\u5b9f\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u306a\u305c\u6cbb\u9a13\u306b\u53c2\u52a0\u3067\u304d\u306a\u3044\u306e\u304b\u3001\u305d\u306e\u80cc\u666f\u306b\u3042\u308b\u533b\u5b66\u7684\u3001\u79d1\u5b66\u7684\u3001\u904b\u55b6\u4e0a\u306e\u7406\u7531\u3092\u5fb9\u5e95\u7684\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002\u3042\u306a\u305f\u306e\u8eab\u4f53\u306e\u7279\u6027\u3084\u751f\u6d3b\u7fd2\u6163\u304c\u3001\u65b0\u85ac\u958b\u767a\u306e\u53b3\u5bc6\u306a\u30eb\u30fc\u30eb\u3068\u3069\u306e\u3088\u3046\u306b\u5408\u81f4\u3057\u306a\u3044\u306e\u304b\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u9a13\u3078\u306e\u7406\u89e3\u3092\u6df1\u3081\u3001\u4eca\u5f8c\u306e\u53c2\u52a0\u691c\u8a0e\u306b\u5f79\u7acb\u3066\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"trial-summary\" data-filter=\"region_kanto\" style=\"background:#f0faf0;border-left:4px solid #43A047;padding:16px 20px;margin:20px 0;border-radius:0 8px 8px 0\"><p style=\"margin:0;color:#333;line-height:1.8\">\u73fe\u5728\u3001\u95a2\u6771\u30a8\u30ea\u30a2\u3067\u306f<strong>12\u4ef6<\/strong>\u306e\u6cbb\u9a13\u30fb\u30e2\u30cb\u30bf\u30fc\u6848\u4ef6\u304c\u52df\u96c6\u4e2d\u3067\u3059\uff08\u8ca0\u62c5\u8efd\u6e1b\u8cbb: 10\u4e073\u5343\u5186\u301c25\u4e07\u5186\uff09\u3002\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u30fb\u975e\u55ab\u7159\u8005\u9650\u5b9a\u30fb\u77ed\u671f\u7b49\u306e\u6848\u4ef6\u304c\u3042\u308a\u307e\u3059\u3002\u5b9f\u65bd\u30a8\u30ea\u30a2\u306f\u95a2\u6771\u30fb\u6771\u4eac\u3067\u3059\u3002<\/p><p style=\"margin:4px 0 0;font-size:0.8em;color:#888\">\u203b2026-04-23\u6642\u70b9\u3002\u6700\u65b0\u72b6\u6cc1\u306f\u8a18\u4e8b\u672b\u5c3e\u306e\u6848\u4ef6\u4e00\u89a7\u3092\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/p><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u9a13\u306e\u300c\u4e0d\u5408\u683c\u300d\u306f\u306a\u305c\u8d77\u3053\u308b\uff1f\u5065\u5eb7\u6210\u4eba\u3067\u3082\u65ad\u3089\u308c\u308b10\u306e\u7406\u7531<\/h2>\n\n\n\n<p>\u65b0\u85ac\u304c\u4e16\u306b\u51fa\u308b\u305f\u3081\u306b\u306f\u3001\u4eba\u4f53\u306b\u521d\u3081\u3066\u85ac\u3092\u6295\u4e0e\u3059\u308b\u300c\u7b2cI\u76f8\u8a66\u9a13\u300d\u3068\u3044\u3046\u91cd\u8981\u306a\u6bb5\u968e\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u8a66\u9a13\u306e\u76ee\u7684\u306f\u3001\u85ac\u306e\u5b89\u5168\u6027\u3084\u3001\u4f53\u5185\u3067\u3069\u306e\u3088\u3046\u306b\u4f5c\u7528\u3059\u308b\u304b\u3092\u7d14\u7c8b\u306b\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u539f\u5247\u3068\u3057\u3066\u5065\u5eb7\u306a\u6210\u4eba\u304c\u5bfe\u8c61\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6cbb\u9a13\u306e\u53c2\u52a0\u57fa\u6e96\uff08\u9664\u5916\u57fa\u6e96\uff09\u306f\u3001\u5927\u304d\u304f\u5206\u3051\u3066\u4e8c\u3064\u306e\u76ee\u7684\u306e\u305f\u3081\u306b\u8a2d\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li> <strong>\u88ab\u9a13\u8005\u306e\u5b89\u5168\u4fdd\u8b77<\/strong>: \u672a\u77e5\u306e\u85ac\u3092\u6295\u4e0e\u3059\u308b\u969b\u3001\u5c11\u3057\u3067\u3082\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u8981\u56e0\u3092\u5fb9\u5e95\u7684\u306b\u6392\u9664\u3059\u308b\u305f\u3081\u3067\u3059\u3002<\/li>\n\n\n\n<li> <strong>\u6b63\u78ba\u306a\u30c7\u30fc\u30bf\u53d6\u5f97<\/strong>: \u85ac\u672c\u6765\u306e\u50cd\u304d\u3092\u6b63\u78ba\u306b\u8a55\u4fa1\u3059\u308b\u305f\u3081\u3001\u30c7\u30fc\u30bf\u306e\u3070\u3089\u3064\u304d\uff08\u30ce\u30a4\u30ba\uff09\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u305f\u3081\u3067\u3059\u3002<\/li>\n<\/ol>\n\n\n\n<p>\u6cbb\u9a13\u306b\u53c2\u52a0\u3067\u304d\u306a\u3044\u4e3b\u306a\u7406\u7531\u306f\u3001\u4ee5\u4e0b\u306e10\u9805\u76ee\u306b\u96c6\u7d04\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u5358\u306a\u308b\u300c\u62d2\u5426\u300d\u3067\u306f\u306a\u304f\u3001\u672a\u6765\u306e\u533b\u7642\u3092\u652f\u3048\u308b\u79d1\u5b66\u7684\u306a\u5fc5\u7136\u6027\u306b\u57fa\u3065\u3044\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u9806\u4f4d<\/th><th>\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u5931\u6557\u306e\u4e3b\u306a\u539f\u56e0<\/th><th>\u767a\u751f\u7387\uff08\u6982\u7b97\uff09<\/th><th>\u4e3b\u306a\u80cc\u666f\u56e0\u5b50<\/th><\/tr><\/thead><tbody><tr><td>1<\/td><td>\u81e8\u5e8a\u691c\u67fb\u5024\uff08\u8840\u6db2\u30fb\u5c3f\uff09\u306e\u7570\u5e38<\/td><td>23.3%<\/td><td>\u809d\u6a5f\u80fd\u3001\u814e\u6a5f\u80fd\u3001\u8102\u8cea\u4ee3\u8b1d\u306e\u9038\u8131<\/td><\/tr><tr><td>2<\/td><td>\u751f\u4f53\u60c5\u5831\uff08\u8840\u5727\u30fb\u8108\u62cd\uff09\u306e\u7570\u5e38<\/td><td>19.3%<\/td><td>\u7dca\u5f35\u306b\u3088\u308b\u9ad8\u8840\u5727\u3001\u5b89\u9759\u6642\u5fc3\u62cd\u306e\u4e0d\u5b89\u5b9a\u3055<\/td><\/tr><tr><td>3<\/td><td>\u5fc3\u96fb\u56f3\u306e\u7570\u5e38<\/td><td>16.6%<\/td><td>\u4e0d\u6574\u8108\u3001QT\u5ef6\u9577\u3001\u8ef8\u504f\u4f4d<\/td><\/tr><tr><td>4<\/td><td>\u6307\u793a\u9075\u5b88\u30fb\u53c2\u52a0\u3078\u306e\u9069\u6027<\/td><td>10-15%<\/td><td>\u55ab\u7159\u6b74\u306e\u865a\u507d\u3001\u9023\u7d61\u306e\u9045\u5ef6\u3001\u6307\u793a\u4e0d\u5c65\u884c<\/td><\/tr><tr><td>5<\/td><td>\u4f53\u683c\u6307\u6570\u30fb\u8eab\u4f53\u7684\u898f\u5b9a<\/td><td>5-10%<\/td><td>\u85ac\u7269\u306e\u4f53\u5185\u5206\u5e03\u3078\u306e\u5f71\u97ff\u3092\u61f8\u5ff5\u3057\u305f\u4f53\u683c\u5236\u9650<\/td><\/tr><tr><td>6<\/td><td>\u904e\u53bb\u306e\u75c5\u6b74\u3084\u8eab\u4f53\u306e\u5f31\u70b9<\/td><td>\uff08\u4e0a\u8a18\u306b\u542b\u307e\u308c\u308b\uff09<\/td><td>\u81d3\u5668\u306e\u4e88\u5099\u80fd\u529b\u4f4e\u4e0b\u3001\u518d\u767a\u30ea\u30b9\u30af<\/td><\/tr><tr><td>7<\/td><td>\u5e38\u7528\u85ac\u30fb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u6442\u53d6<\/td><td>\uff08\u4e0a\u8a18\u306b\u542b\u307e\u308c\u308b\uff09<\/td><td>\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u306e\u30ea\u30b9\u30af<\/td><\/tr><tr><td>8<\/td><td>\u907a\u4f1d\u7684\u306a\u4f53\u8cea\u30fb\u6c11\u65cf\u7684\u80cc\u666f<\/td><td>\uff08\u4e0a\u8a18\u306b\u542b\u307e\u308c\u308b\uff09<\/td><td>\u85ac\u7269\u4ee3\u8b1d\u9175\u7d20\u306e\u6d3b\u6027\u5dee<\/td><\/tr><tr><td>9<\/td><td>\u751f\u6b96\u306b\u95a2\u3059\u308b\u5b89\u5168\u6027\u3068\u5bb6\u65cf\u8a08\u753b<\/td><td>\uff08\u4e0a\u8a18\u306b\u542b\u307e\u308c\u308b\uff09<\/td><td>\u80ce\u5150\u3078\u306e\u5f71\u97ff\u30ea\u30b9\u30af<\/td><\/tr><tr><td>10<\/td><td>\u691c\u67fb\u51e6\u7f6e\u3078\u306e\u4e0d\u9069\u683c\u6027<\/td><td>\uff08\u4e0a\u8a18\u306b\u542b\u307e\u308c\u308b\uff09<\/td><td>MRI\u691c\u67fb\u6642\u306e\u30bf\u30c8\u30a5\u30fc\u3001\u63a1\u8840\u56f0\u96e3<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u306e\u30c7\u30fc\u30bf\u304b\u3089\u3082\u308f\u304b\u308b\u901a\u308a\u3001\u533b\u5b66\u7684\u306a\u6570\u5024\u306b\u3088\u308b\u9664\u5916\u304c\u904e\u534a\u6570\u3092\u5360\u3081\u307e\u3059\u304c\u3001\u751f\u6d3b\u7fd2\u6163\u3084\u884c\u52d5\u7279\u6027\u306b\u8d77\u56e0\u3059\u308b\u9664\u5916\u3082\u7121\u8996\u3067\u304d\u306a\u3044\u5272\u5408\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u3042\u306a\u305f\u306e\u300c\u5065\u5eb7\u300d\u3068\u6cbb\u9a13\u306e\u300c\u5065\u5eb7\u300d\u306f\u9055\u3046\uff1f\u533b\u5b66\u7684\u691c\u67fb\u5024\u306e\u58c1<\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1396\" src=\"https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-scaled.jpg\" alt=\"\u898b\u51fa\u30571\u7528: \u300e\u5065\u5eb7\u306a\u306e\u306b\u6cbb\u9a13\u306b\u843d\u3061\u305f\u300f\u3042\u306a\u305f\u3078\u3002\u53c2\u52a0\u3067\u304d\u306a\u304410\u306e\u7406\u7531\u3068\u3001\u305d\u306e\u88cf\u306b\u3042\u308b\u79d1\u5b66\u7684\u771f\u5b9f - \u30a4\u30e1\u30fc\u30b8\u30a4\u30e9\u30b9\u30c8\" class=\"wp-image-2343\" srcset=\"https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-scaled.jpg 2560w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-300x164.jpg 300w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-1024x559.jpg 1024w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-768x419.jpg 768w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-1536x838.jpg 1536w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611362797-1-2048x1117.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" 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https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611369702-2-300x164.jpg 300w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611369702-2-1024x559.jpg 1024w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611369702-2-768x419.jpg 768w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611369702-2-1536x838.jpg 1536w, https:\/\/chiken-net.site\/column\/wp-content\/uploads\/2026\/03\/article-1772611369702-2-2048x1117.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" 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class=\"wp-block-heading\">\u4eba\u7a2e\u30fb\u6c11\u65cf\u7684\u306a\u4f53\u8cea\u306e\u9055\u3044\uff08\u65e5\u672c\u4eba\u898f\u5b9a\uff09<\/h3>\n\n\n\n<p>\u65e5\u672c\u3067\u5b9f\u65bd\u3055\u308c\u308b\u6cbb\u9a13\u306e\u591a\u304f\u306b\u306f\u300c\u4e21\u89aa\u304a\u3088\u3073\u7956\u7236\u6bcd\u304c\u65e5\u672c\u4eba\u3067\u3042\u308b\u3053\u3068\u300d\u3068\u3044\u3046\u898f\u5b9a\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u56fd\u969b\u7684\u306a\u533b\u5b66\u57fa\u6e96\u306b\u304a\u3044\u3066\u3001\u4eba\u7a2e\u9593\u306e\u907a\u4f1d\u7684\u306a\u4f53\u8cea\u306e\u9055\u3044\u304c\u85ac\u7269\u4ee3\u8b1d\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u7121\u8996\u3067\u304d\u306a\u3044\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u85ac\u7269\u4ee3\u8b1d\u9175\u7d20\u306e\u6d3b\u6027\u306b\u306f\u4eba\u7a2e\u5dee\u304c\u3042\u308a\u3001\u7279\u306b\u30a2\u30b8\u30a2\u4eba\u306f\u6b27\u7c73\u4eba\u306b\u6bd4\u3079\u3066\u3001\u7279\u5b9a\u306e\u9175\u7d20\uff08CYP2C19\u306a\u3069\uff09\u306e\u6d3b\u6027\u304c\u4f4e\u3044\u300c\u85ac\u7269\u306e\u4ee3\u8b1d\u304c\u9045\u3044\u4f53\u8cea\u300d\u306e\u5272\u5408\u304c\u9ad8\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u4ee3\u8b1d\u9175\u7d20<\/th><th>\u65e5\u672c\u4eba\u306e\u4ee3\u8b1d\u304c\u9045\u3044\u4f53\u8cea\u306e\u5272\u5408<\/th><th>\u85ac\u7406\u5b66\u7684\u306a\u610f\u7fa9<\/th><\/tr><\/thead><tbody><tr><td>CYP2C19<\/td><td>\u7d0420%<\/td><td>\u7279\u5b9a\u306e\u85ac\u7269\u304c\u5206\u89e3\u3055\u308c\u306b\u304f\u304f\u3001\u526f\u4f5c\u7528\u304c\u51fa\u3084\u3059\u3044<\/td><\/tr><tr><td>CYP2D6<\/td><td>\u4f4e\u983b\u5ea6<\/td><td>\u93ae\u75db\u5264\u306a\u3069\u306e\u52b9\u679c\u306b\u5dee\u304c\u51fa\u308b\u3053\u3068\u304c\u3042\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u6d77\u5916\u3067\u627f\u8a8d\u3055\u308c\u305f\u85ac\u3092\u65e5\u672c\u3067\u5c0e\u5165\u3059\u308b\u969b\u3001\u65e5\u672c\u4eba\u306e\u4f53\u8cea\u3067\u3082\u540c\u69d8\u306e\u5b89\u5168\u6027\u30fb\u6709\u52b9\u6027\u304c\u5f97\u3089\u308c\u308b\u304b\u3092\u78ba\u8a8d\u3059\u308b\u300c\u30d6\u30ea\u30c3\u30b8\u30f3\u30b0\u8a66\u9a13\u300d\u306b\u304a\u3044\u3066\u3001\u88ab\u9a13\u8005\u306b\u4ed6\u306e\u6c11\u65cf\u306e\u8840\u304c\u6df7\u3058\u3063\u3066\u3044\u308b\u3068\u3001\u7d14\u7c8b\u306a\u65e5\u672c\u4eba\u96c6\u56e3\u3068\u3057\u3066\u306e\u30c7\u30fc\u30bf\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u305a\u3001\u627f\u8a8d\u7533\u8acb\u4e0a\u306e\u6839\u62e0\u304c\u5f31\u307e\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 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class=\"wp-block-heading\">\u691c\u67fb\u51e6\u7f6e\u3078\u306e\u8eab\u4f53\u7684\u30fb\u5fc3\u7406\u7684\u306a\u4e0d\u9069\u683c\u6027<\/h3>\n\n\n\n<p>\u533b\u5b66\u7684\u306b\u5065\u5eb7\u3067\u3042\u3063\u3066\u3082\u3001\u6cbb\u9a13\u3067\u4e88\u5b9a\u3055\u308c\u3066\u3044\u308b\u300c\u51e6\u7f6e\u300d\u305d\u306e\u3082\u306e\u304c\u5b9f\u65bd\u56f0\u96e3\u306a\u5834\u5408\u306f\u3001\u53c2\u52a0\u3092\u65ad\u3089\u3056\u308b\u3092\u5f97\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p><strong>\u30bf\u30c8\u30a5\u30fc\uff08\u5165\u308c\u58a8\uff09\u3068\u78c1\u6c17\u5171\u9cf4\u753b\u50cf\u8a3a\u65ad\u88c5\u7f6e\uff08MRI\uff09\u306e\u30ea\u30b9\u30af<\/strong> 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\u7b2cI\u76f8\u8a66\u9a13\u3067\u306f\u3001\u85ac\u7269\u306e\u4f53\u5185\u3067\u306e\u52d5\u304d\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u3001\u77ed\u6642\u9593\u306b\u4f55\u5ea6\u3082\u63a1\u8840\u3092\u884c\u3046\u300c\u983b\u56de\u63a1\u8840\u300d\u304c\u3042\u308a\u307e\u3059\u3002\u8840\u7ba1\u304c\u7d30\u304f\u3001\u91dd\u3092\u523a\u3059\u306e\u304c\u8457\u3057\u304f\u56f0\u96e3\u306a\u88ab\u9a13\u8005\u306f\u3001\u533b\u7642\u30b9\u30bf\u30c3\u30d5\u306b\u904e\u5ea6\u306a\u8ca0\u62c5\u3092\u304b\u3051\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u4e88\u5b9a\u3055\u308c\u305f\u6642\u9593\u901a\u308a\u306b\u63a1\u8840\u304c\u3067\u304d\u305a\u3001\u30c7\u30fc\u30bf\u306e\u7cbe\u5ea6\u3092\u843d\u3068\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u91dd\u306b\u5bfe\u3059\u308b\u904e\u5ea6\u306e\u6050\u6016\u5fc3\u3084\u3001\u63a1\u8840\u6642\u306b\u8133\u8ca7\u8840\uff08\u8840\u7ba1\u8ff7\u8d70\u795e\u7d4c\u53cd\u5c04\uff09\u3092\u8d77\u3053\u3057\u3084\u3059\u3044\u4f53\u8cea\u306e\u65b9\u3082\u3001\u88ab\u9a13\u8005\u306e\u5b89\u5168\u4fdd\u8b77\u306e\u89b3\u70b9\u304b\u3089\u53c2\u52a0\u3092\u65ad\u3089\u308c\u308b\u306e\u304c\u4e00\u822c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5065\u5eb7\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u6cbb\u9a13\u3067\u4e0d\u9069\u683c\u3068\u5224\u65ad\u3055\u308c\u308b\u3053\u3068\u306f\u3001\u6c7a\u3057\u3066\u3042\u306a\u305f\u304c\u4e0d\u5065\u5eb7\u3067\u3042\u308b\u3053\u3068\u3084\u4eba\u9593\u6027\u306b\u554f\u984c\u304c\u3042\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u305b\u3093\u3002\u3053\u308c\u3089\u306e\u53b3\u683c\u306a\u9664\u5916\u57fa\u6e96\u306f\u3001\u88ab\u9a13\u8005\u306e\u5b89\u5168\u3092\u6700\u5927\u9650\u306b\u4fdd\u8b77\u3057\u3001\u65b0\u85ac\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3092\u79d1\u5b66\u7684\u306b\u8a3c\u660e\u3059\u308b\u305f\u3081\u306e\u300c\u5fc5\u7136\u6027\u300d\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6cbb\u9a13\u306f\u3001\u88ab\u9a13\u8005\u306e\u751f\u547d\u4fdd\u8b77\u3001\u79d1\u5b66\u7684\u306a\u7d14\u5ea6\u306e\u8ffd\u6c42\u3001\u305d\u3057\u3066\u793e\u4f1a\u7684\u306a\u4fe1\u983c\u6027\u306e\u62c5\u4fdd\u3068\u3044\u3046\u4e09\u3064\u306e\u67f1\u306b\u3088\u3063\u3066\u6210\u308a\u7acb\u3063\u3066\u3044\u307e\u3059\u3002\u6cbb\u9a13\u306b\u53c2\u52a0\u3067\u304d\u306a\u3044\u3068\u5224\u65ad\u3055\u308c\u308b\u3053\u3068\u306f\u3001\u3042\u304f\u307e\u3067\u300c\u305d\u306e\u7279\u5b9a\u306e\u8a66\u9a13\u306e\u5b9f\u65bd\u8a08\u753b\u66f8\u3068\u3044\u3046\u6975\u3081\u3066\u7279\u6b8a\u306a\u74b0\u5883\u300d\u306b\u304a\u3044\u3066\u3001\u79d1\u5b66\u7684\u30fb\u5b89\u5168\u7684\u306a\u30d4\u30fc\u30b9\u3068\u3057\u3066\u9069\u5408\u3059\u308b\u304b\u3069\u3046\u304b\u306e\u5224\u65ad\u306b\u904e\u304e\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u6cbb\u9a13\u306f\u672a\u6765\u306e\u533b\u7642\u3092\u7bc9\u304f\u305f\u3081\u306e\u91cd\u8981\u306a\u793e\u4f1a\u8ca2\u732e\u6d3b\u52d5\u3067\u3059\u3002\u4eca\u56de\u306e\u89e3\u8aac\u3092\u901a\u3058\u3066\u3001\u6cbb\u9a13\u306e\u4ed5\u7d44\u307f\u3068\u3001\u306a\u305c\u3053\u308c\u307b\u3069\u307e\u3067\u306b\u53b3\u5bc6\u306a\u57fa\u6e96\u304c\u8a2d\u3051\u3089\u308c\u3066\u3044\u308b\u306e\u304b\u3092\u3054\u7406\u89e3\u3044\u305f\u3060\u3051\u305f\u306a\u3089\u5e78\u3044\u3067\u3059\u3002\u8a73\u7d30\u306a\u53c2\u52a0\u6761\u4ef6\u306f\u3001\u5404\u6cbb\u9a13\u306e\u52df\u96c6\u30da\u30fc\u30b8\u3067\u78ba\u8a8d\u3067\u304d\u307e\u3059\u306e\u3067\u3001\u3054\u81ea\u8eab\u306e\u72b6\u6cc1\u3068\u7167\u3089\u3057\u5408\u308f\u305b\u3066\u691c\u8a0e\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p><strong>\u6cbb\u9a13\u30cd\u30c3\u30c8\u306b\u3064\u3044\u3066<\/strong><\/p>\n\n\n\n<p>\u300c\u6642\u9593\u3092\u3001\u4fa1\u5024\u306b\u5909\u3048\u308b\u3002\u672a\u6765\u3092\u3001\u5065\u5eb7\u3067\u3064\u306a\u3050\u3002\u300d<\/p>\n\n\n\n<p>\u6cbb\u9a13\u30cd\u30c3\u30c8\u306f\u3001\u6cbb\u9a13\u3078\u306e\u53c2\u52a0\u3092\u300c\u6642\u9593\u306e\u6295\u8cc7\u300d\u3068\u6349\u3048\u3001\u7d0d\u5f97\u3067\u304d\u308b\u60c5\u5831\u63d0\u4f9b\u3092\u5927\u5207\u306b\u3057\u3066\u3044\u307e\u3059\u3002\u30ef\u30af\u30c1\u30f3\u30fb\u751f\u6d3b\u7fd2\u6163\u75c5\u30fb\u7f8e\u5bb9\u306a\u3069\u5e45\u5e83\u3044\u5206\u91ce\u306e\u52df\u96c6\u60c5\u5831\u3092\u63b2\u8f09\u4e2d\u3002\u4f1a\u54e1\u767b\u9332\uff08\u7121\u6599\uff09\u3067\u3001\u3042\u306a\u305f\u306e\u6761\u4ef6\u306b\u5408\u3063\u305f\u6848\u4ef6\u3092\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u2192 <a href=\"https:\/\/chiken-net.site\/entry\">\u4f1a\u54e1\u767b\u9332\u30da\u30fc\u30b8\u3078<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u53c2\u8003\u30fb\u51fa\u5178<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u65b0\u533b\u85ac\u54c1\u306e\u81e8\u5e8a\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u4e00\u822c\u6307\u91dd\u306b\u3064\u3044\u3066( \u5e73\u621004\u5e7406\u670829 &#8230;\uff08\u539a\u751f\u52b4\u50cd\u7701\u306b\u3088\u308b\u65b0\u533b\u85ac\u54c1\u306e\u81e8\u5e8a\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u6307\u91dd\u3002\uff09 https:\/\/www.mhlw.go.jp\/web\/t_doc?dataId=00ta7179&amp;dataType=1&amp;pageNo=1<\/li>\n\n\n\n<li>A retrospective study: screening failure analysis of 1058 healthy volunteers in phase I clinical trials &#8211; PubMed\uff08\u7b2cI\u76f8\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3051\u308b\u5065\u5eb7\u6210\u4eba\u5fd7\u9858\u8005\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u5931\u6557\u8981\u56e0\u306b\u95a2\u3059\u308b\u7814\u7a76\u8ad6\u6587\u3002\uff09 https:\/\/pubmed.ncbi.nlm.nih.gov\/35927780\/<\/li>\n\n\n\n<li>A retrospective study: screening failure analysis of 1058 healthy volunteers in phase I clinical trials &#8211; Annals of Palliative Medicine\uff08\u7b2cI\u76f8\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3051\u308b\u5065\u5eb7\u6210\u4eba\u5fd7\u9858\u8005\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u5931\u6557\u8981\u56e0\u306b\u95a2\u3059\u308b\u7814\u7a76\u8ad6\u6587\u3002\uff09 https:\/\/apm.amegroups.org\/article\/view\/98712\/html<\/li>\n\n\n\n<li>Inclusion\/Exclusion Criteria &#8211; Boxer Lab\uff08\u6cbb\u9a13\u306e\u9078\u629e\u30fb\u9664\u5916\u57fa\u6e96\u306b\u95a2\u3059\u308b\u60c5\u5831\u3002\uff09 https:\/\/boxerlab.ucsf.edu\/treatment-trials\/participate-trial\/inclusionexclusion-criteria<\/li>\n\n\n\n<li>Public Workshop: EVALUATING INCLUSION AND EXCLUSION CRITERIA IN CLINICAL TRIALS &#8211; Food and Drug Administration\uff08FDA\u306b\u3088\u308b\u81e8\u5e8a\u8a66\u9a13\u306e\u9078\u629e\u30fb\u9664\u5916\u57fa\u6e96\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u8cc7\u6599\u3002\uff09 https:\/\/www.fda.gov\/media\/134754\/download<\/li>\n\n\n\n<li>Phase I Clinical Trials Explained: Objectives, Risks &amp; Process &#8211; CCRPS\uff08\u7b2cI\u76f8\u81e8\u5e8a\u8a66\u9a13\u306e\u76ee\u7684\u3001\u30ea\u30b9\u30af\u3001\u30d7\u30ed\u30bb\u30b9\u306b\u95a2\u3059\u308b\u89e3\u8aac\u3002\uff09 https:\/\/ccrps.org\/clinical-research-blog\/phase-i-clinical-trials-explained-objectives-risks-amp-process<\/li>\n\n\n\n<li>\u30ec\u30ca\u30ea\u30c9\u30df\u30c9\u30ab\u30d7\u30bb\u30eb 5 mg\u300c\u30b5\u30ef\u30a4\u300d\u306e \u5065\u5eb7\u6210\u4eba\u306b\u304a\u3051\u308b\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\uff08\u5065\u5eb7\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u751f\u7269\u5b66\u7684\u540c\u7b49\u6027\u8a66\u9a13\u306e\u5831\u544a\u66f8\u3002\uff09 https:\/\/www.shinryo-to-shinyaku.com\/db\/pdf\/sin_0060_04_0217.pdf<\/li>\n\n\n\n<li>\u6cbb\u9a13\u306e\u4f11\u85ac\u671f\u9593\u306e\u5fc5\u8981\u6027\u306b\u3064\u3044\u3066\u89e3\u8aac\uff08\u6cbb\u9a13\u306e\u4f11\u85ac\u671f\u9593\u306e\u5fc5\u8981\u6027\u306b\u95a2\u3059\u308b\u89e3\u8aac\u8a18\u4e8b\u3002\uff09 https:\/\/www.media-ctms.com\/basic\/drug-holiday.html<\/li>\n\n\n\n<li>\u533b\u7642\u6a5f\u95a2\u306e\u516c\u958b\u60c5\u5831\uff08\u30bf\u30d0\u30b3\u3068\u85ac\u306e\u95a2\u4fc2\u306b\u95a2\u3059\u308b\u60c5\u5831\u3002\uff09 https:\/\/www.hospital.iwata.shizuoka.jp\/medicine\/001\/<\/li>\n\n\n\n<li>\u533b\u7642\u6a5f\u95a2\u306e\u516c\u958b\u60c5\u5831\uff08\u85ac\u3068\u55ab\u7159\u306b\u95a2\u3059\u308b\u60c5\u5831\u3002\uff09 https:\/\/www.himemaria.or.jp\/maria\/departments\/pharmacy_trivia\/trivia15.html<\/li>\n\n\n\n<li>CYP1A2\u3067\u4ee3\u8b1d\u3055\u308c\u308b\u533b\u85ac\u54c1\uff0b\u55ab\u7159\uff08\u305f\u3070\u3053\uff09\uff3b\u30c9\u30af\u30bf\u30fc\u306e\u305f\u3081\u306e\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u3068\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\uff089\uff09\uff3d\uff08CYP1A2\u9175\u7d20\u3068\u55ab\u7159\u306b\u3088\u308b\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u306b\u95a2\u3059\u308b\u5c02\u9580\u8a18\u4e8b\u3002\uff09 https:\/\/www.jmedj.co.jp\/blogs\/product\/product_1014<\/li>\n\n\n\n<li>\u6cbb\u9a13\u306b\u65e5\u672c\u4eba\u306e\u53c2\u52a0\u8005\u304c\u5fc5\u8981\u306a\u7406\u7531 | Altasciences LA\uff08\u6cbb\u9a13\u306b\u65e5\u672c\u4eba\u306e\u53c2\u52a0\u8005\u304c\u5fc5\u8981\u306a\u7406\u7531\u306b\u95a2\u3059\u308b\u89e3\u8aac\u3002\uff09 https:\/\/participantsla.altasciences.com\/jp\/blog\/why-japanese-participants-are-needed-for-clinical-trial<\/li>\n\n\n\n<li>MRI\u3067\u5165\u308c\u58a8\uff08\u523a\u9752\u3001\u30bf\u30c8\u30a5\u30fc\uff09\u3084\u30a2\u30fc\u30c8\u30e1\u30a4\u30af\u306f\u306a\u305c\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u306e\u3067\u3059\u304b\uff1f\uff08MRI\u691c\u67fb\u6642\u306e\u30bf\u30c8\u30a5\u30fc\u306b\u95a2\u3059\u308b\u6ce8\u610f\u70b9\u3002\uff09 https:\/\/gazo.or.jp\/column\/mri\/16312\/<\/li>\n\n\n\n<li>\u6cbb\u9a13\u306b\u304a\u3051\u308b\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u5bfe\u5fdc\u306e\u5c02\u9580\u7684\u57fa\u6e96\uff08\u6cbb\u9a13\u306b\u304a\u3051\u308b\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u5bfe\u5fdc\u306e\u5c02\u9580\u7684\u57fa\u6e96\u306b\u95a2\u3059\u308bPDF\u8cc7\u6599\u3002\uff09 https:\/\/www.pref.gunma.jp\/uploaded\/attachment\/156392.pdf<\/li>\n<\/ul>\n\n\n\n<h2 style=\"color:#43A047;font-size:1.4em;margin-bottom:16px;border-bottom:3px solid #43A047;padding-bottom:8px\">\u95a2\u6771\u30a8\u30ea\u30a2\u306e\u52df\u96c6\u4e2d\u6848\u4ef6<\/h2>\n\n\n\n<table style=\"width:100%;border-collapse:collapse;background:#fff;border-radius:8px;overflow:hidden;box-shadow:0 1px 3px rgba(0,0,0,0.08)\"><thead><tr style=\"background:#43A047;border-bottom:2px solid #43A047\"><th style=\"padding:14px;text-align:left;color:#fff;font-weight:600;font-size:0.9em\">\u6848\u4ef6\u540d<\/th><th style=\"padding:14px;text-align:left;color:#fff;font-weight:600;font-size:0.9em\">\u5730\u57df<\/th><th style=\"padding:14px;text-align:left;color:#fff;font-weight:600;font-size:0.9em\">\u5bfe\u8c61<\/th><th style=\"padding:14px;text-align:left;color:#fff;font-weight:600;font-size:0.9em\">\u8ca0\u62c5\u8efd\u6e1b\u8cbb<\/th><th style=\"padding:14px;text-align:left;color:#fff;font-weight:600;font-size:0.9em\">\u65e5\u7a0b<\/th><th style=\"padding:14px;text-align:center;color:#fff;font-weight:600;font-size:0.9em\">\u72b6\u6cc1<\/th><\/tr><\/thead><tbody>\n<tr style=\"background:#fff;border-bottom:1px solid #e8e8e8\"><td style=\"padding:12px 14px\"><a href=\"https:\/\/chiken-net.site\/products\/detail\/1003192\" target=\"_blank\" rel=\"noopener\" style=\"color:#2e7d32;text-decoration:none;font-weight:500\">\u77ed\u671f\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u6cbb\u9a13\uff085\u670817\u65e5\uff5e\uff09<\/a><\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u95a2\u6771<\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u5973\u6027<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-weight:500\">220,000\u5186<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-size:0.9em\">4\u6cca\u00d72\u56de<\/td><td style=\"padding:12px 14px;text-align:center\"><span style=\"color:#fff;background:#43A047;padding:2px 10px;border-radius:4px;font-size:0.85em;font-weight:bold\">\u52df\u96c6\u4e2d<\/span><\/td><\/tr>\n<tr style=\"background:#fff;border-bottom:1px solid #e8e8e8\"><td style=\"padding:12px 14px\"><a href=\"https:\/\/chiken-net.site\/products\/detail\/1003144\" target=\"_blank\" rel=\"noopener\" style=\"color:#2e7d32;text-decoration:none;font-weight:500\">\u77ed\u671f\u6cbb\u9a13\uff085\u67082\u65e5\uff5e\uff09<\/a><\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u95a2\u6771<\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u7537\u6027<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-weight:500\">127,000\u5186<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-size:0.9em\">2\u6cca\u00d72\u56de+\u30e1\u30fc\u30eb\u9023\u7d615\u56de<\/td><td style=\"padding:12px 14px;text-align:center\"><span style=\"color:#fff;background:#43A047;padding:2px 10px;border-radius:4px;font-size:0.85em;font-weight:bold\">\u52df\u96c6\u4e2d<\/span><\/td><\/tr>\n<tr style=\"background:#fff;border-bottom:1px solid #e8e8e8\"><td style=\"padding:12px 14px\"><a href=\"https:\/\/chiken-net.site\/products\/detail\/1003077\" target=\"_blank\" rel=\"noopener\" style=\"color:#2e7d32;text-decoration:none;font-weight:500\">\u77ed\u671f\u6cbb\u9a13\uff085\u67088\u65e5\uff5e\uff09<\/a><\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u95a2\u6771<\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u7537\u6027<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-weight:500\">127,000\u5186<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-size:0.9em\">2\u6cca\u00d72\u56de+\u30e1\u30fc\u30eb\u9023\u7d615\u56de<\/td><td style=\"padding:12px 14px;text-align:center\"><span style=\"color:#fff;background:#43A047;padding:2px 10px;border-radius:4px;font-size:0.85em;font-weight:bold\">\u52df\u96c6\u4e2d<\/span><\/td><\/tr>\n<tr style=\"background:#fff;border-bottom:1px solid #e8e8e8\"><td style=\"padding:12px 14px\"><a href=\"https:\/\/chiken-net.site\/products\/detail\/1002961\" target=\"_blank\" rel=\"noopener\" style=\"color:#2e7d32;text-decoration:none;font-weight:500\">\u55ab\u7159\u8005\u53ef\uff085\u670813\u65e5\uff5e\uff09<\/a><\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u95a2\u6771<\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u5973\u6027<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-weight:500\">210,000\u5186<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-size:0.9em\">8\u6cca\uff0b\u901a\u96621\u56de<\/td><td style=\"padding:12px 14px;text-align:center\"><span style=\"color:#fff;background:#43A047;padding:2px 10px;border-radius:4px;font-size:0.85em;font-weight:bold\">\u52df\u96c6\u4e2d<\/span><\/td><\/tr>\n<tr style=\"background:#fff;border-bottom:1px solid #e8e8e8\"><td style=\"padding:12px 14px\"><a href=\"https:\/\/chiken-net.site\/products\/detail\/1002843\" target=\"_blank\" rel=\"noopener\" style=\"color:#2e7d32;text-decoration:none;font-weight:500\">\u7247\u982d\u75db\u3067\u304a\u60a9\u307f\u306e\u5c0f\u5150\uff086\uff5e17\u6b73\uff09\u306e\u65b9<\/a><\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u95a2\u6771<\/td><td style=\"padding:12px 14px;white-space:nowrap\">\u7537\u6027<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-weight:500\">\u5fdc\u52df\u5f8c\u958b\u793a<\/td><td style=\"padding:12px 14px;white-space:nowrap;font-size:0.9em\">\u6700\u957719\u9031\u9593<\/td><td style=\"padding:12px 14px;text-align:center\"><span style=\"color:#fff;background:#43A047;padding:2px 10px;border-radius:4px;font-size:0.85em;font-weight:bold\">\u52df\u96c6\u4e2d<\/span><\/td><\/tr>\n<\/tbody><\/table>\n\n\n\n<p 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